Review finds no clear increase in side effects with intrathecal immunotherapy
A review of 201 patients found fewer severe adverse-event episodes with intrathecal treatment, but the comparison was small, indirect and dominated by melanoma cases.
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Naproxen exposure associated with ovarian changes in rat study
A 100-day experiment found lower progesterone, reduced antioxidant activity and changes in developing ovarian follicles, but it did not test fertility in people.
Review finds vine tea extracts active against bacteria and fungi
A narrative review reports activity in laboratory and animal studies, while warning that inconsistent tests and limited safety data block clinical conclusions.
Nickel-foam catalyst holds high current for more than 100 hours
A laboratory study links the result to charge shifts and a changing surface, while leaving full-scale electrolyzer tests open.
Study ties TRIM59 to bladder cancer progression and PTRF turnover
Higher TRIM59 tracked with advanced disease and shorter survival, while cell and mouse experiments linked it to growth, invasion and PTRF protein turnover. Treatment response was not tested.
Study links chronic chemical stress to smaller stress granules
A Preprint study reports weaker MYH9-G3BP1 binding and fewer contacts between stress granules and P-bodies in cells exposed to repeated stress.
Review finds promise in new treatments for discoid lupus
A peer-reviewed review of 84 articles says targeted drugs may help resistant disease, but much of the evidence comes from mixed lupus populations.
Mouse study links HS1BP3 to T-cell memory and energy use
The preclinical work tied the protein to mitochondrial energy production, but it did not test HS1BP3-engineered cells in patients.
Fruit and Vegetable Intake Linked to Fewer First Bladder Cancer Recurrences
A Dutch cohort study found the association three months after diagnosis, but the observational results do not show that diet prevents cancer from returning or advancing.
Mouse study ties macrophage PABPC4 to colorectal cancer growth
In mice, Pabpc4 knockout was linked to smaller tumors and stronger CD8+ T-cell activity; human data showed associations, not clinical benefit.
Bacteria-loaded gel improved fertility in rats after uterine injury
Injured rats treated with the injectable material developed a thicker uterine lining and produced about 11 newborns on average, while controls produced none.
Lead-free capacitors convert heat into electricity in lab tests
The devices reached 3.7 joules per cubic centimetre across a 170 K span, with the strongest 10 K window at 40 to 50 °C.
European ADHD clinicians flag gaps in personalised care guidance
A survey of 1,441 clinicians in 23 European countries identifies three broad needs, including better treatment personalisation evidence and guidance in local languages.
Hip DXA scans closely tracked femur screw strength in cadaver study
In a laboratory test of 20 cadaveric femurs, hip-specific DXA matched newer bone-quality measures in tracking screw pullout strength, but the findings do not set a rule for patients.
Researchers find small, salt-sensitive alpha-synuclein assemblies
A peer-reviewed laboratory study reports a low-salt state that is finite, chemically fragile and reversible, while higher salt was linked to larger assemblies.
Study finds polymer-copper binder performs better in sulfur batteries
In laboratory lithium-sulfur cells, the copper-linked binder retained more capacity at fast test rates and reached 7.3 mAh per square centimetre at a 9 mg per square centimetre sulfur loading.
Fatty pancreas found in a third of pancreatic cyst patients
A matched case-control study found no statistically significant overall link to pancreatic cystic lesions, while a possible signal in the pancreatic tail needs larger studies.
Leaf-made zinc oxide nanoparticles show strong corrosion inhibition
In laboratory tests on carbon steel in 1 M hydrochloric acid, both routes showed high reported inhibition at 100 ppm, but they ranked differently across electrochemical tests.
Nanoparticles linked to calmer microglia and better stroke recovery
A study in cells and mice associated sulfonated nanoparticles with less inflammatory signaling and improved neurological measures after ischemic stroke.
Loss of CYLD linked to DNA repair shift and Olaparib sensitivity
Laboratory experiments tied chromosome 16q loss to lower CYLD, greater DNA damage and a repair pattern associated with greater sensitivity to the PARP inhibitor Olaparib.