A modeling study links fluctuating plankton growth and dispersal to abundance distributions, spatial correlations, Taylor scaling and patchiness, while exposing clear limits in seasonal and oligotrophic data.
A Qatar hospital study found widespread DNA-methylation differences associated with preterm birth in maternal peripheral blood and neonatal cord blood. Most signals were tissue-specific, with a smaller set shared between mothers and newborns.
Frontiers in epigenetics and epigenomics4 min read
A phase-resolved study of cultured mouse stem cells found that compartment strength rose abruptly at the start of S phase, with stronger A-A contacts and a more consolidated strong-A signal.
A review of 31 studies involving 6,157 Chinese pregnant women found a recurring pattern of gut-microbiota differences in those with gestational diabetes, but large variation between studies limits what the findings can say about cause, screening or treatment.
A 24-hour study in differentiated SH-SY5Y cells found DHA had the strongest PSD-95 and glutamatergic protein responses, while EPA and mixed compositions showed weaker or distinct profiles.
Researchers identified 137 UGT genes in Rhododendron simsii and found that RiUGT43 transcripts were more abundant in darker flowers and associated with anthocyanin differences in transient petal tests.
Researchers report that oligozoospermic sperm with high reactive oxygen species showed extensive, mostly reduced DNA methylation differences, although only eight samples were profiled and the study cannot establish cause or clinical benefit.
A longitudinal mouse study found that gut bacterial communities showed different patterns across methamphetamine exposure and abstinence, with time patterns that require independent validation before they can support prediction.
A short treatment of donor cells was associated with fewer signs of graft-versus-host disease and higher survival in fully mismatched mice, with similar findings in a haploidentical model. The study tested cells and animals, not patients, and did not directly assess anti-tumour activity.
The findings support treating Camellia sections Eriandria and Theopsis as one genetic group, but they do not establish why their ovary surfaces differ.
A retrospective study found that persistent high-risk HPV after LEEP was associated with residual or recurrent HSIL, while multiple infection, menopause and positive endocervical margins were linked to HPV persistence.
The study paired electrical recordings with endpoint payload measurements in human iPSC-derived sensory neurons and found different activity patterns among three antibody-drug conjugates.
A single-center retrospective cohort found that non-cryopreserved grafts were linked with similar engraftment and overall survival to cryopreserved grafts. Hospital stays were shorter, but mucositis was more frequent, and the non-randomized design limits causal conclusions.
The experiment found broad cross-resistance in Candida tropicalis cultures exposed to agricultural azoles, alongside changes in DNA content, gene copy number and gene activity.
A study of two TBEV strains found that Hypr NS1 engaged JAM-A in protein and cell assays more strongly than Vs NS1, while predicted claudin contacts remain untested.
Foliar treatments with epibrassinolide, melatonin, potassium phosphate, or a mixture of all three were linked with higher wheat yields and dry matter under natural heat stress after flowering. The results varied by season and came from one cultivar at one field location.
Three rosemary monoterpenes affected the human serotonin transporter in engineered cells, but the partial, high-concentration effect does not establish antidepressant activity.
Higher GPER1 expression was associated with longer overall survival among younger women in a retrospective tumor analysis, while laboratory results pointed to cell-cycle changes that need further testing.
Researchers found coordinated changes in fibrosis markers, SOCS3 methylation and JAK2/STAT3 signaling in rat vocal-fold fibroblasts from injured animals and after TGF-β1 exposure. The 5-aza findings point to a possible pathway, but the laboratory work does not establish cause and effect or human treatment relevance.
World journal of otorhinolaryngology - head and neck surgery3 min read
In 89 cattle, an antibody-coated membrane assay classified faecal samples similarly to nested PCR, but the single-herd, subclinical sample leaves its wider performance uncertain.
ReplicateFest recovered every reported FEST-expanded clonotype in an HIV-1 reanalysis, but simulations showed that weak expansions and low-frequency clones were easier to miss.
In one healthy Chinese person with discordant ABO typing, researchers identified a novel variant and used minigene experiments and computational modeling to examine its splicing and that of two reported variants.
In 240 female Huoyan geese, the lowest N-carbamylglutamate dose was associated with higher body weight from week six and faster average daily gain between weeks four and eight.
A study of 103 young stud boars found breed-specific changes in fecal microbial diversity and community structure during and after a short course of dietary amoxicillin. Large White and Landrace boars had their lowest measured diversity during treatment, while Duroc showed no significant time-point differences in the diversity measures.
A study of petal cells found more epidermis-enriched genes, layer-exclusive expression changes and PhDEF binding sites in the epidermis than in the mesophyll. The results suggest that cell-layer context may shape how PhDEF operates, but they do not prove that every bound gene is regulated by PhDEF.
Virus-free lineage tracing, live imaging and single-cell analysis found no sign that sustained NeuroD1 expression converted mouse microglia into neurons. The labeled cells instead remained microglia or disappeared, with increased cell death and autophagy-related changes.
A single infusion of edited blood-forming stem cells was associated with donor-cell engraftment and better movement, cerebellar, heart and pancreatic measures in humanized Friedreich’s ataxia mice. The findings were incomplete and remain preclinical, with some abnormalities persisting and the proposed editing threshold not prospectively validated.
A 30-patient study found that multidrug-resistant tuberculosis was associated with lower microbial diversity and a distinct lower-airway microbiome, while a six-genus classifier showed promising but preliminary performance.
A large CMOS capacitance sensor tracked label-free movement from individual cells to cancer-cell spheroids and millimetre-scale engineered tissues, while offering a much wider field than the optical comparison.
A computational study finds that bee-like colonies can evolve shared directional signals when food is neither too scarce nor too easy to find, and that a later shift to a gravity-referenced code can remain viable under many tested settings.
A preprint study of Vanessa cardui reports shared and divergent gene functions in segmentation, suggesting that butterflies use a limited and reshaped regulatory network.
A paper asks what accounts for ion-mobility differences between GRGDS and SDGRG, but the supplied sectioned text contains no methods, sample details or study results.
A review says Phase 1 trials have repeatedly expanded VRC01-class precursors in humans, while broad, potent serum antibodies and memory B cells remain the harder test.
Researchers combined five new genome assemblies, a published genome, population-level sequence data and ATAC-seq profiles to track genetic and chromatin differences across Heliconius erato. The strongest association appeared at intermediate divergence, while two hybrid-zone tests were not significant.
An analysis of 497 sampled fish found a strong genetic divide between Northern and Southern Hemisphere groups, with additional structure among Mexican fish and differences between selected captive stocks and wild populations.
MARLOWE ranked microbial contributors well in controlled tests, but its results were less reliable for secondary sources and less specific than MiCId in the broader comparison.
GPS tracking linked reinforcers that joined resident birds with slower dispersal and larger core ranges than birds that stayed in an exclusive reinforcer group. Survival to 55 days did not differ significantly, and the observational design could not show that social integration caused the movement patterns.