Specialty
A study of two TBEV strains found that Hypr NS1 engaged JAM-A in protein and cell assays more strongly than Vs NS1, while predicted claudin contacts remain untested.
ACS omega4 min read
Virus-free lineage tracing, live imaging and single-cell analysis found no sign that sustained NeuroD1 expression converted mouse microglia into neurons. The labeled cells instead remained microglia or disappeared, with increased cell death and autophagy-related changes.
eLife4 min read
A multicenter cohort study found breastfeeding status up to 6 months was associated with lower influenza risk during the first year, but the design cannot show cause and effect.
Pediatric research4 min read
A tissue study of four fatal DENV-4 cases from Ceará’s 2012 dengue epidemic found abnormalities in the liver, lungs and kidneys, while the hearts examined were largely preserved. TNF-α and IFN-γ staining was detected in liver, lung and kidney tissue. The qualitative study cannot estimate risk, prognosis or the frequency of these findings.
Memorias do Instituto Oswaldo Cruz5 min read