Subject
Genes, genomes, epigenetics, variation, and inheritance.
A Qatar hospital study found widespread DNA-methylation differences associated with preterm birth in maternal peripheral blood and neonatal cord blood. Most signals were tissue-specific, with a smaller set shared between mothers and newborns.
Frontiers in epigenetics and epigenomics4 min read
Researchers identified 137 UGT genes in Rhododendron simsii and found that RiUGT43 transcripts were more abundant in darker flowers and associated with anthocyanin differences in transient petal tests.
Frontiers in plant science4 min read
Researchers report that oligozoospermic sperm with high reactive oxygen species showed extensive, mostly reduced DNA methylation differences, although only eight samples were profiled and the study cannot establish cause or clinical benefit.
Frontiers in reproductive health4 min read
The findings support treating Camellia sections Eriandria and Theopsis as one genetic group, but they do not establish why their ovary surfaces differ.
Frontiers in plant science4 min read
Higher GPER1 expression was associated with longer overall survival among younger women in a retrospective tumor analysis, while laboratory results pointed to cell-cycle changes that need further testing.
Frontiers in endocrinology4 min read
Researchers found coordinated changes in fibrosis markers, SOCS3 methylation and JAK2/STAT3 signaling in rat vocal-fold fibroblasts from injured animals and after TGF-β1 exposure. The 5-aza findings point to a possible pathway, but the laboratory work does not establish cause and effect or human treatment relevance.
World journal of otorhinolaryngology - head and neck surgery3 min read
A complete comparison of two Caenorhabditis genomes found a 29.9% size gap, with satellite DNA accounting for over 30% of their sequence differences.
Genome research4 min read
A preprint study of Vanessa cardui reports shared and divergent gene functions in segmentation, suggesting that butterflies use a limited and reshaped regulatory network.
Development (Cambridge, England)3 min read
Researchers combined five new genome assemblies, a published genome, population-level sequence data and ATAC-seq profiles to track genetic and chromatin differences across Heliconius erato. The strongest association appeared at intermediate divergence, while two hybrid-zone tests were not significant.
Science advances5 min read
A laboratory study links chromosome 16q loss and CYLD depletion to genomic instability, a shift in DNA repair and greater Olaparib sensitivity in cancer models, while tissue and public-data results remain associative.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)5 min read
The assemblies shared a conserved gene layout and showed strong species-level clustering, but the mitochondrial data did not settle wider Carabidae relationships.
Ecology and evolution4 min read
TPT1 showed the strongest single-gene separation between sarcopenia and control samples in two bulk muscle-transcriptomic cohorts, while mouse and cell experiments showed matching protein changes. The findings remain exploratory and do not establish causation, disease specificity, or clinical usefulness.
Frontiers in cell and developmental biology4 min read