Specialty
A short treatment of donor cells was associated with fewer signs of graft-versus-host disease and higher survival in fully mismatched mice, with similar findings in a haploidentical model. The study tested cells and animals, not patients, and did not directly assess anti-tumour activity.
Frontiers in immunology4 min read
The study paired electrical recordings with endpoint payload measurements in human iPSC-derived sensory neurons and found different activity patterns among three antibody-drug conjugates.
Frontiers in toxicology4 min read
In 89 cattle, an antibody-coated membrane assay classified faecal samples similarly to nested PCR, but the single-herd, subclinical sample leaves its wider performance uncertain.
Veterinary medicine and science4 min read
ReplicateFest recovered every reported FEST-expanded clonotype in an HIV-1 reanalysis, but simulations showed that weak expansions and low-frequency clones were easier to miss.
Frontiers in immunology4 min read
In one healthy Chinese person with discordant ABO typing, researchers identified a novel variant and used minigene experiments and computational modeling to examine its splicing and that of two reported variants.
Frontiers in immunology4 min read
A review says Phase 1 trials have repeatedly expanded VRC01-class precursors in humans, while broad, potent serum antibodies and memory B cells remain the harder test.
Current opinion in HIV and AIDS3 min read
In six experimentally infected beagles, trūRapid FOUR first detected heartworm antigen at week 20 after heat treatment and was positive in all six by week 22.
Parasites & vectors4 min read
A prospective hospital study found that two dried-blood-spot devices closely matched paired serum results for anti-Trypanosoma cruzi antibodies, but low-index positives were sometimes missed.
PLoS neglected tropical diseases4 min read