The study also found distinct cerebrospinal-fluid biomarker patterns and a clinical prediction model that performed well within the same cohort, but its observational design does not establish cause.
The Brazilian MADRS performed consistently in a clinical sample, but the study found that a lower score may suit screening while a higher score better balances sensitivity and specificity. The findings need testing in other settings.
International journal of methods in psychiatric research4 min read
A small, single-center study found lower pain and state-anxiety scores after medical termination, while average post-procedural comfort was classified as moderate.
Revista da Associacao Medica Brasileira (1992)3 min read
A study of the nucleus accumbens core reports strong facilitation from thalamic inputs and marked depression from cortical inputs, with both AMPA and NMDA receptors contributing to the responses.
The Journal of neuroscience : the official journal of the Society for Neuroscience3 min read
A randomized colonoscopy trial reported lower anxiety with pink noise and lower pain with both noise types than with control, but it did not give numerical effect sizes.
The study found that physical-somatic complaints shaped depressive symptom scores after spinal cord injury, while changes in clinically relevant symptoms showed no apparent association with neurological or functional recovery.
Adolescents who reported more parental communication also reported fewer anxiety and depression symptoms, while paternal neglect was linked to more symptoms. The study also identified cognitive flexibility as the most consistent possible statistical pathway.
A Chongqing survey of 10,112 workers found wide industry differences in reported depressive, anxiety and combined symptoms, with physical pain and occupational stress showing the strongest adjusted associations.