A phase-resolved study of cultured mouse stem cells found that compartment strength rose abruptly at the start of S phase, with stronger A-A contacts and a more consolidated strong-A signal.
A single infusion of edited blood-forming stem cells was associated with donor-cell engraftment and better movement, cerebellar, heart and pancreatic measures in humanized Friedreich’s ataxia mice. The findings were incomplete and remain preclinical, with some abnormalities persisting and the proposed editing threshold not prospectively validated.
A large CMOS capacitance sensor tracked label-free movement from individual cells to cancer-cell spheroids and millimetre-scale engineered tissues, while offering a much wider field than the optical comparison.