Zinc oxide nanoparticles made with olive-leaf extract were most active against HepG-2 liver cancer cells in cell tests, while their effects on normal cells underscored the need for further safety work.
A mixed-methods study found that only task completion time differed clearly from zero after correction for multiple testing. Interviews suggested different strategies across exploratory performance profiles, but the findings are descriptive and cannot establish causes.
A multicenter Spanish study found that all 34 categories tested in a proposed framework for primary care physical therapy exceeded a preset retention threshold. Patient and therapist ratings were often close overall, although individual differences remained.
In a randomized trial at a tertiary hospital in central India, women who received two warm compressions at the lower back had lower pain scores at later checks than those given routine care.
The study also found distinct cerebrospinal-fluid biomarker patterns and a clinical prediction model that performed well within the same cohort, but its observational design does not establish cause.
An analysis of lung-cancer safety reports found positive myotoxicity reporting signals for nivolumab, pembrolizumab and atezolizumab, but not durvalumab. Fatal outcomes appeared in 20.1% of reports, while the database could not estimate incidence or prove causation.
A longitudinal analysis found different within-person associations, but it cannot show that physical activity or smartphone use caused changes in how adolescents rated their body shape.
A western-Kenya comparison found higher administrative coverage for campaign-based treatment than for treatment delivered through routine primary health care.
A meta-analysis of 12 randomized trial publications found higher reported response rates and lower tinnitus and anxiety scores in acupuncture-based treatment groups, while biomarker results were inconclusive.
A small study found that Azure Kinect tracked some shoulder and elbow movements well, but overestimated postoperative shoulder flexion and external rotation compared with an IMU reference.
Frontiers in bioengineering and biotechnology4 min read
A Qatar hospital study found widespread DNA-methylation differences associated with preterm birth in maternal peripheral blood and neonatal cord blood. Most signals were tissue-specific, with a smaller set shared between mothers and newborns.
Frontiers in epigenetics and epigenomics4 min read
Among 2,001 high-thrombotic-risk STEMI patients treated with PCI, those who received post-PCI PACT had similar observed outcomes to those who did not, but the observational study could not establish equivalence.
A study of 118 participants found that greater distance from an inferred stranger preference was linked to higher accuracy, while a predicted curved effect disappeared after adjustment.
Research on biologic therapy for Crohn’s disease grew steadily over the decade, while newer work increasingly centered on biomarkers, prediction and treatment comparisons.
A randomized trial in 296 adults with septic shock reported lower 28-day mortality after anisodamine was added to standard therapy, but it did not establish that changes in lactate caused the difference.
A study combining ovarian tumor data, survival modeling and cell experiments found that SPP1-related patterns tracked with poorer outcomes and changed after PI3 silencing in laboratory models.
An analysis of 19 healthy participants found that the centre of the upper-arm bone moved an average of 4.9 millimetres during recorded shoulder motions, with differences between people. Motion type was associated with translation, while the tested handheld load was not.
A study of 139 Beijing adults found strong internal performance when machine-learning models separated phlegm-dampness and balanced constitutions, but larger validation is still needed.
A phase-resolved study of cultured mouse stem cells found that compartment strength rose abruptly at the start of S phase, with stronger A-A contacts and a more consolidated strong-A signal.
People whose health vulnerability rose between two assessments had the highest observed cardiovascular disease risk in a 16,072-person UK Biobank analysis. Over a median 8.9 years, 3,033 first cardiovascular events were recorded.
A five-feature model based on exercise-test measurements showed high discrimination for both acute mountain sickness and symptom severity after rapid ascent. The result came from a retrospective cohort with internal testing, so it does not establish how well the tool would work in broader populations.
A review of 31 studies involving 6,157 Chinese pregnant women found a recurring pattern of gut-microbiota differences in those with gestational diabetes, but large variation between studies limits what the findings can say about cause, screening or treatment.
A 24-hour study in differentiated SH-SY5Y cells found DHA had the strongest PSD-95 and glutamatergic protein responses, while EPA and mixed compositions showed weaker or distinct profiles.
A study of clinical malaria isolates and humanized mice found that P. malariae was associated with young red blood cells and could be detected in immature bone-marrow cells. The result broadens the picture of where the parasite may persist, but the marrow evidence came from mice, not human patients.
A Chinese cohort analysis found that higher baseline intrinsic-capacity deficit scores were associated with less favorable BADL and IADL trajectories over 10 years. The BADL rate effect was small, while the primary IADL rate estimate was not statistically significant and changed under missing-data assumptions.
Participants reported higher scores for performance and satisfaction on personally prioritized activities, while broader measures of recovery and care experience did not show statistically significant change.
Researchers found that LINC00887 tracked with higher glycolysis, M2 macrophage polarization and weaker CD8+ T-cell activity in clear cell kidney cancer models. Lowering the RNA slowed tumors in mice, while reducing UPF1 reversed the pattern.
Students who met more of three 24-hour movement guidelines tended to report better positive mental health, with university adaptation and resilience making up part of the statistical association.
A qualitative study identified barriers to perinatal mental-health support and six participant-proposed priorities for making services easier to find, reach and use.
Researchers identified 137 UGT genes in Rhododendron simsii and found that RiUGT43 transcripts were more abundant in darker flowers and associated with anthocyanin differences in transient petal tests.
Frontiers in plant science4 min read
Showing 30 of 413 articles
Research fields
Explore science by topic
Start broad, then move into one of thirty focused subject desks.