An automated fluorescence video system detected D. immitis microfilariae more often than a manual wet mount in diluted blood, but the evidence came from one infected donor and one uninfected animal.
A review of published evidence says clinicians should consider mycobacterial infection when a prosthetic-joint infection is culture-negative, indolent, or does not respond to conventional antibacterial therapy. It recommends prolonged culture and individualized care combining surgery with species-directed multidrug therapy.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology3 min read
Among 254 hospitalized adults receiving immune-modulating treatment, vaccinated patients had shorter hospital stays and lower observed mortality than unvaccinated patients. The findings show an association, not proof of a causal effect.
A study of 52 dengue patients found two plasma microRNAs associated with warning-sign status and reported strong diagnostic performance, while key accuracy measures and prospective validation are still missing.
A structured review of 12 clinical studies involving 794 patients reported higher diagnostic yields for metagenomic next-generation sequencing than for culture-based testing in infective endocarditis. The authors describe the pooled estimates as illustrative and call for standardised testing and randomised trials.
Researchers detected DNA from Listeria monocytogenes and Salmonella enteritidis in roughly half of pooled egg samples in Assiut, Egypt. Salmonella DNA was more common than Listeria DNA in stool samples from diarrheic patients, but PCR could not show whether the bacteria were alive or whether eggs infected people.
In 172,422 adults who underwent posterior lumbar interbody fusion, those with a preoperative epidural injection had slightly more infections and nerve injuries, while dural leaks did not differ significantly.