Subject
Microbes, viruses, immune systems, infection, and host response.
A review of 31 studies involving 6,157 Chinese pregnant women found a recurring pattern of gut-microbiota differences in those with gestational diabetes, but large variation between studies limits what the findings can say about cause, screening or treatment.
Frontiers in nutrition4 min read
A longitudinal mouse study found that gut bacterial communities showed different patterns across methamphetamine exposure and abstinence, with time patterns that require independent validation before they can support prediction.
Frontiers in microbiology4 min read
A short treatment of donor cells was associated with fewer signs of graft-versus-host disease and higher survival in fully mismatched mice, with similar findings in a haploidentical model. The study tested cells and animals, not patients, and did not directly assess anti-tumour activity.
Frontiers in immunology4 min read
The study paired electrical recordings with endpoint payload measurements in human iPSC-derived sensory neurons and found different activity patterns among three antibody-drug conjugates.
Frontiers in toxicology4 min read
The experiment found broad cross-resistance in Candida tropicalis cultures exposed to agricultural azoles, alongside changes in DNA content, gene copy number and gene activity.
Mycology3 min read
A study of two TBEV strains found that Hypr NS1 engaged JAM-A in protein and cell assays more strongly than Vs NS1, while predicted claudin contacts remain untested.
ACS omega4 min read
In 89 cattle, an antibody-coated membrane assay classified faecal samples similarly to nested PCR, but the single-herd, subclinical sample leaves its wider performance uncertain.
Veterinary medicine and science4 min read
ReplicateFest recovered every reported FEST-expanded clonotype in an HIV-1 reanalysis, but simulations showed that weak expansions and low-frequency clones were easier to miss.
Frontiers in immunology4 min read
In one healthy Chinese person with discordant ABO typing, researchers identified a novel variant and used minigene experiments and computational modeling to examine its splicing and that of two reported variants.
Frontiers in immunology4 min read
In 240 female Huoyan geese, the lowest N-carbamylglutamate dose was associated with higher body weight from week six and faster average daily gain between weeks four and eight.
Frontiers in veterinary science3 min read
A study of 103 young stud boars found breed-specific changes in fecal microbial diversity and community structure during and after a short course of dietary amoxicillin. Large White and Landrace boars had their lowest measured diversity during treatment, while Duroc showed no significant time-point differences in the diversity measures.
Frontiers in veterinary science4 min read
Virus-free lineage tracing, live imaging and single-cell analysis found no sign that sustained NeuroD1 expression converted mouse microglia into neurons. The labeled cells instead remained microglia or disappeared, with increased cell death and autophagy-related changes.
eLife4 min read
A 30-patient study found that multidrug-resistant tuberculosis was associated with lower microbial diversity and a distinct lower-airway microbiome, while a six-genus classifier showed promising but preliminary performance.
Annals of medicine5 min read
A review says Phase 1 trials have repeatedly expanded VRC01-class precursors in humans, while broad, potent serum antibodies and memory B cells remain the harder test.
Current opinion in HIV and AIDS3 min read
Vine tea’s main flavonoid, dihydromyricetin, has shown reported activity against bacteria and fungi in laboratory studies, and some formulations performed better than the free compound. But the evidence is uneven, with no standardized dose, limited direct proof of how the compound works, and safety data that do not answer questions about human use.
Medical science monitor : international medical journal of experimental and clinical research4 min read
A multicenter cohort study found breastfeeding status up to 6 months was associated with lower influenza risk during the first year, but the design cannot show cause and effect.
Pediatric research4 min read
A laboratory study combines microscopy and SSU rDNA analysis to identify Vairimorpha aylae in infected Cydalima perspectalis larvae collected in Bilecik.
Acta parasitologica3 min read
In six experimentally infected beagles, trūRapid FOUR first detected heartworm antigen at week 20 after heat treatment and was positive in all six by week 22.
Parasites & vectors4 min read
A prospective hospital study found that two dried-blood-spot devices closely matched paired serum results for anti-Trypanosoma cruzi antibodies, but low-index positives were sometimes missed.
PLoS neglected tropical diseases4 min read
In young moon jellyfish, treatments that changed the animals’ bacterial community coincided with more frequent arm regeneration. The results point to a possible role for arginine-related metabolism, but model predictions and short-term laboratory tests do not establish how the process works.
PloS one4 min read
A tissue study of four fatal DENV-4 cases from Ceará’s 2012 dengue epidemic found abnormalities in the liver, lungs and kidneys, while the hearts examined were largely preserved. TNF-α and IFN-γ staining was detected in liver, lung and kidney tissue. The qualitative study cannot estimate risk, prognosis or the frequency of these findings.
Memorias do Instituto Oswaldo Cruz5 min read