Specialty
All four adults stayed on treatment, but the retrospective report included selected responders and cannot establish a causal treatment effect.
Frontiers in pharmacology4 min read
A prospective, open-label study reported that two people with chronic stroke-related upper-limb impairment completed long-term myoelectric virtual-reality training, while changes in motor function remained preliminary.
Frontiers in rehabilitation sciences4 min read
A small, single-group study found that MINDSET 2.0 met its prespecified feasibility criteria, while leaving unanswered whether the tool improves health or connects people with recommended support.
Frontiers in neurology3 min read
A laboratory cell study found that proteins linked to Alzheimer’s disease were not engaged uniformly by macroautophagy. Phosphorylated tau showed the largest reported abundance change and a high LC3-associated fraction, while amyloid-beta showed limited engagement.
Frontiers in neuroscience4 min read
A survey of US adults already taking rimegepant found sex-related differences in reported reasons and triggers for short-term prevention, but it did not test efficacy.
Frontiers in neurology4 min read
A mouse experiment found that induced hypertension did not significantly intensify alpha-synuclein-linked dopaminergic neuron loss, glial responses or most inflammatory signals.
Frontiers in immunology3 min read
A qualitative review found Grade A recommendations for several cognitive, exercise, memory and stimulation approaches, while the evidence was too varied for pooled treatment effects.
Frontiers in neurology4 min read
The evidence did not demonstrate that oral melatonin reduced multiple sclerosis activity, disability progression or new MRI activity, and possible symptom benefits remain uncertain.
Frontiers in neurology3 min read
The study found a clear rise in documented end-of-life preferences as death approached, with the timing and completeness of records differing sharply between care settings. The findings describe chart documentation, not the full timing of conversations or the effect of planning on care.
Journal of Parkinson's disease : Duplicate, marked for deletion4 min read
In 753 adults with traumatic brain injury, higher TRIAGES scores were associated with unfavorable function at discharge and slightly outperformed admission GCS in the same cohort. The findings do not validate a general clinical cutoff.
Frontiers in neurology4 min read
In a network analysis of stroke patient-spouse dyads, several fear-of-progression dimensions were associated with lower patient self-care or spouse contributions, but the data cannot establish cause and effect.
The journal of nursing research : JNR4 min read
In a prospective cohort, I-FABP and MMP-9 fell over seven days among patients receiving enteral nutrition and rose among those receiving parenteral nutrition, but the study cannot show that the route caused the difference.
Annals of Saudi medicine4 min read
An analysis of 96 fatal pediatric traumatic brain injury cases found that traffic accidents involved mainly adolescents, while abusive head trauma was concentrated in children aged two or younger.
International journal of legal medicine5 min read
In 66 recordings from 22 children, scalp high-frequency oscillations were more common in hypsarrhythmia groups and occurred at higher rates than in IED groups. The authors say the measures may complement EEG assessment, but are not ready to stand alone.
Experimental physiology5 min read
Alpha-synuclein showed properties consistent with small, micelle-like assemblies in low-salt laboratory conditions, while higher salt was linked to larger clusters, condensates and some fibrils over time.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)4 min read
The findings point to endosomal acidity, the pH inside cell compartments called endosomes, as a possible way to influence harmful microglial activity after stroke. The evidence remains preclinical and does not establish a treatment for people.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)5 min read
In a surgical cohort with MRI-detected hemorrhage and edema, preoperative IHL and early postoperative AMS recovery rate were reported as independent predictors of six-month neurological recovery.
Acta neurologica Belgica4 min read
The observational study found smaller IA volume across MS phenotypes and an association with executive dysfunction, but it did not establish cause or clinical usefulness.
Journal of neurology4 min read
A real-world European cohort selected for reducing other antiseizure medicines while taking cenobamate showed substantial seizure reductions, but its small, nonrandomized groups limit what can be concluded.
Epilepsia open5 min read
A review maps AI-based approaches to autism diagnosis and identifies small samples, uneven imaging protocols and limited population diversity as barriers to generalizability.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology3 min read