An analysis of 96 fatal pediatric traumatic brain injury cases found that traffic accidents involved mainly adolescents, while abusive head trauma was concentrated in children aged two or younger.
In 66 recordings from 22 children, scalp high-frequency oscillations were more common in hypsarrhythmia groups and occurred at higher rates than in IED groups. The authors say the measures may complement EEG assessment, but are not ready to stand alone.
Alpha-synuclein showed properties consistent with small, micelle-like assemblies in low-salt laboratory conditions, while higher salt was linked to larger clusters, condensates and some fibrils over time.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)4 min read
The findings point to endosomal acidity, the pH inside cell compartments called endosomes, as a possible way to influence harmful microglial activity after stroke. The evidence remains preclinical and does not establish a treatment for people.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)5 min read
In a surgical cohort with MRI-detected hemorrhage and edema, preoperative IHL and early postoperative AMS recovery rate were reported as independent predictors of six-month neurological recovery.
The observational study found smaller IA volume across MS phenotypes and an association with executive dysfunction, but it did not establish cause or clinical usefulness.
A real-world European cohort selected for reducing other antiseizure medicines while taking cenobamate showed substantial seizure reductions, but its small, nonrandomized groups limit what can be concluded.
A review maps AI-based approaches to autism diagnosis and identifies small samples, uneven imaging protocols and limited population diversity as barriers to generalizability.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology3 min read