Specialty
A survey of healthcare professionals highlights organizational and patient-facing barriers to delivering prehabilitation for people with pancreatic cancer.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer3 min read
Patients carefully chose family caregivers for a web-based support programme, linking the decision to caregiver burden and hopes for difficult conversations.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer4 min read
Orange-peel-mediated zinc oxide nanoparticles showed activity against selected microbial isolates and cancer cell lines in laboratory assays. The findings do not establish treatment efficacy or safety in people.
Scientific reports5 min read
Compound 2 reacted less with an 8mer DNA model than Compound 1, DDP and OxPt, but limited mass-spectrometry evidence could not establish where it attached or whether the pattern would hold in living systems.
Bioinorganic chemistry and applications4 min read
Researchers found several ovarian changes in female rats given environmentally relevant naproxen exposure, alone or in a chemical mixture. The results raise a reproductive-risk question without establishing human effects.
Clinical and experimental reproductive medicine4 min read
A study found higher TRIM59 expression in bladder cancer tissues and cell lines, with links to advanced clinical features and shorter survival. Experiments connected TRIM59 to PTRF protein turnover and cancer-cell growth and invasion, but did not test treatment response.
Cancer science4 min read
A mouse study with human colorectal cancer data points to a macrophage PABPC4-SPP1 pathway linked to tumor growth and immune suppression, but it does not test a treatment in patients.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)4 min read
Among 2,604 cancer survivors transitioned to primary care, 440 later had an oncology visit, and recurrence or new disease was detected in 4.8% of the full cohort.
Journal of cancer survivorship : research and practice3 min read
In a 40-hip comparison after pelvic radiotherapy, trabecular metal cups were linked with higher revision-free survivorship than reconstruction cages, although the authors describe the findings as hypothesis-generating.
International orthopaedics4 min read
In radioiodine-refractory differentiated thyroid cancer, Pentixafor and FDG PET/CT detected similar proportions of lesions, but FDG had higher median uptake measures overall.
Molecular imaging and biology3 min read
A 48-patient retrospective study found that PET-derived heterogeneity, metabolic tumor volume and total lesion glycolysis were associated with Ryan 3 poor pathological response after chemoradiotherapy, though the findings do not establish causation.
Annals of nuclear medicine4 min read
In a 714-patient analysis, small tumors did not show higher complete-response rates, while larger tumors were linked to more residual disease.
Annals of surgical oncology3 min read
Most practitioners considered quality-of-life assessment important for treatment planning and informed decisions, yet only two of 10 described regular use of formal tools.
Laryngoscope investigative otolaryngology4 min read
A SINEUP-based RNA tool was associated with a more hepatocyte-like gene, protein and metabolic profile in Huh7-based three-dimensional microtissues. The study also found higher reported CYP activity and mixed responses to drug exposures, while the authors said the model still needs further validation.
Journal of liver cancer4 min read
The study reports a candidate plasma marker that distinguished colorectal cancer from comparison groups internally and a laboratory model connecting the RNA to altered mitochondrial translation and succinate.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)5 min read
Researchers used onion-peel extract to make O3, a zinc oxide preparation tested on human A549 lung adenocarcinoma cells. The cells showed lower viability and associated changes in morphology, cell-cycle distribution, ROS and p53 localization, but the findings do not establish clinical efficacy or safety.
Frontiers in chemistry4 min read