Specialty
A systematic review found no clear excess of side effects when intrathecal immune checkpoint inhibitors were added to systemic treatment for leptomeningeal disease, while survival differences remained uncertain.
Neurosurgical review5 min read
Researchers found a scattered set of genetic candidates, while warning that the evidence is too limited to identify a definitive cause.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery3 min read
Researchers say inflammation linked to cerebral palsy can persist beyond the perinatal period, with higher levels associated with greater severity in the studies reviewed.
Pediatric research4 min read
A meta-analysis of seven studies found altered timing and occupancy of resting brain states in ASD, alongside promising but highly variable classification performance.
Journal of autism and developmental disorders4 min read
The review found myelitis and optic neuritis were the leading reported presentations, while corticosteroids and treatment discontinuation were common and favorable outcomes were reported in 71.7% of cases. Because the evidence came from published case reports and case series, it does not estimate incidence or compare treatments.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology3 min read
A systematic review of six randomized trials involving 105 participants found that most studies reported gains in comprehension, word processing and language performance, but differences between trials limited direct comparisons.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology4 min read
The evidence points to several ways complement regulators may help glioma cells avoid immune attack and support proliferation, invasion or treatment resistance, while leaving clinical benefit unproven.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico4 min read
A systematic review found that vascular graft and endograft infections after abdominal aortic aneurysm repair were uncommon but relevant complications. Its pooled incidence estimate was lower after EVAR than open surgery, but wide variation in diagnostic criteria and limited microbiological data for OS make the comparison harder to interpret.
Infection3 min read